When consumed together, the effects of alcohol and drugs: Do you currently have car insurance? Insurance is mandatory to drive in South carolina Yes I have insurance. But please show me your best quotes. No, please help me find the best insurance. Question When consumed together, the effects of alcohol and drugs: Answers Are less dangerous than when either is consumed alone. Are usually minimal. Can be more pronounced than when either is consumed alone. Often balance out. Explanation Many drugs, including prescription and over-the-counter medications, can impair your ability to ride safely. Some medications become even more dangerous when combined with alcohol.