Who may operate a vehicle that requires placards to be driven? Question Who may operate a vehicle that requires placards to be driven? Answers Any driver with a CDL A driver with a hazardous materials endorsement A driver with a minimum of 10 years of commercial driving experience Any person who thinks they can Explanation You must have a CDL with a HazMat endorsement to operate a vehicle that is used to transport hazardous materials. This questions appears in the following tests: New Jersey Class A Knowledge Test Wyoming Class B Knowledge Test